MF

C₂₁H₃₀O₅

MW

362.46

Function

Anti-inflammatory

Basic Organisms

Absidia orchidis

Precursor

cortexolone

Host

Saccharomyces cerevisiae

Synthesis Type

Complete biosynthesis

Downstream Gene

CYP5311B2,ClCDR4

Pathway

Reference

Chen J, Fan F, Qu G, et al. Identification of Absidia orchidis steroid 11β-hydroxylation system and its application in engineering Saccharomyces cerevisiae for one-step biotransformation to produce hydrocortisone[J]. Metabolic engineering, 2020, 57: 31-42.